Pharmaceutical Raw Materials Chemical Powder GMP Captopril CAS 62571-86-2

• CAS No.: 62571-86-2
• Formula: C9h15no3s
• EINECS: 263-607-1
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: CAS 62571-86-2
• Colour: White
• Assay: 99%+
• Storage: Cool and Dry
• Molecular Weight: 217.29
• Grade: Pharmaceutical Grade
• Application: Sineptina
• Package: Bottle.Box, Barrel
• Other Item: CAS 979-32-8 Estradiol Valerate CAS 4956-37-0
• Another Item: Algestone Acetophenide 24356-94-3/Acetylsalicylic
• CAS: 151-73-5
• Other Name: Irbesartan
• Others: Pantoprazole CAS 102625-70-7
• Another Name: Pantoprazole Sodium CAS 138786-67-1
• Addition: L (+) -Asparagine Monohydrate
• Brand: Kanal
• Product Name: Pimobendan
• Transport Package: Glass Bottle, Plastic Bottle, Foil Bag, Carton
• Specification: Packaging can be customized
• Trademark: KANAL
• Origin: China
• Production Capacity: 8000kg/Month

Product Description

Product Name	Captopril
CAS	62571-86-2
Synonyms	(2S)-1-[(2S)-3-Mercapto-2-methylpropionyl]-2-pyrrolidinecarboxylic acid;1-[(S)-3-Mercapto-2-methylpropionyl]-L-proline;Captopril,N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline;Captopril (200 mg);Captopril API;Captopril Cardiovascular;(S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline (S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline;3-Mercapto-2-Methylpropanoic acid 1,2-diphenylethylaMine salt (MMPA)
Appearance	White or almost white crystalline powder
Molecular Formula	C9H15NO3S
Molecular Weight	217.29
Assay	99%+
Application	For research purpose only
Packing	25kg/drum

Description:
Captopril, 1-[(2S)-3-mercapto-2-methyl-1-oxopropionyl]proline (Capoten), blocks the conversion of angiotensinI to angiotensin II by inhibiting the convertingenzyme. The rational development of captopril as an inhibitorof ACE was based on the hypothesis that ACE and carboxypeptidaseA functioned by similar mechanisms. It wasnoted that d-2-benzylsuccinic acid was a potent inhibitor ofcarboxypeptidase A, but not ACE. By use of this small molecule as a prototype, captopril was designed with a carboxylgroup on a proline and a thiol group was introduced toenhance the binding to the zinc ion of ACE. The importantbinding points at the active site of ACE are thought to be anarginine residue, which provides a cationic site that attracts acarboxylate ion, and a zinc ion, which can polarize a carbonylgroup of an amide function to make it more susceptible to hydrolysis.Hydrophobic pockets lie between these groups in theactive site, as does a functional group that forms a hydrogenbond with an amide carbonyl.
Function:
Orally active angiotensin-converting enzyme (ACE) inhibitor

 

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.